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How does Fildena Super Active 100 Mg work? Sildenafil citrate is an enzyme called phosphodiesterase (PDE-5) and the active ingredient in Fildena Super Active 100 Mg, which usually works against the symptoms of erectile dysfunction by increasing blood flow to the penis. It relaxes the blood vessels of the penis in men. The enzyme is also useful in pulmonary hypertension, as it relaxes the blood vessels in the lungs and allows the blood to flow more smoothly.